De nol children

In the treatment of diseases of the stomach are often used drugs based on bismuth, which include De-Nol. Is this medicine allowed in childhood and how to take it correctly?

The drug is available in solid form, represented by coated cream-white film-coated tablets. They are round and convex on both sides. The medicine has no smell, but sometimes the tablet smells slightly of ammonia. One blister contains 8 tablets, and one pack can contain 7 or 14 blisters.

The main component that has a therapeutic effect of the drug is bismuth in the form of tri-potassium dicitrate (this compound is also called bismuth sub citrate). If you count its amount on bismuth oxide, then each tablet will contain 120 mg of such oxide. Drug content also includes macrogol 6000, potassium polyacrylate, magnesium stearate, corn starch, and povidone K30. For the manufacture of shell tablets using macrogol and hypromellose.

The bismuth compound in the composition of the tablets has an antiseptic and astringent effect. He also has bactericidal activity against Helicobacter pylori. In addition, the drug reduces the severity of inflammation in the gastric mucosa.

Once in the acidic environment of the digestive tract, bismuth forms chelate compounds, which, like a protective film, cover erosions and ulcers. Under the influence of the drug, the synthesis of mucus and prostaglandin E is normalized, and other protective mechanisms are activated, due to which the stomach walls become more resistant to hydrochloric acid and enzymes.

In bismuth also note the property to reduce the activity of pepsin produced in the stomach. Also, this metal stimulates the accumulation in the damaged tissues of a special factor that stimulates cell regeneration. At the same time, in the digestive tract, the drug is almost not absorbed, but leaves the body with feces. That small amount of bismuth, which penetrates through the walls of the stomach into the blood, is excreted by the kidneys.

Most often, De-Nol children prescribed for peptic ulcer disease, which hit the stomach or 12 duodenal ulcer. The drug is indicated during an exacerbation, especially if the disease is provoked by Helicobacter.

In addition, the tablets are written out:

• With gastritis in chronic form, when it is exacerbated.
• With chronic gastroduodenitis.
• With irritable bowel syndrome, manifested by diarrhea.
• When dyspepsia functional nature.

Tablets do not give if:

• The child has serious problems with kidney function.
• A small patient showed an intolerance to bismuth or other ingredients.

• The digestive system of the child may respond to pills with nausea, increased stool, constipation or vomiting. As a rule, these side effects are temporary and not dangerous.
• Due to the formation of bismuth sulfide in the body, taking pills can cause a darker feces color, as well as a slight darkening of the tongue.
• In some patients, the drug provokes allergies.Most often it is itchy skin or a rash.
• If tablets are given for a long time, encephalopathy may develop due to the accumulation of bismuth in the nerve tissues.

• The pill should be swallowed with a small amount of water. For 30 minutes before taking the medicine and 30 minutes after that you cannot eat food and liquids, especially milk, fruit juices and fresh fruit.
• For a 4-8 year old child, the dosage is calculated by weight. For every kilogram of body weight per day you need 8 mg of bismuth compound. For example, a 5-year-old child weighs 17 kg, which means that the estimated dosage is 136 mg, that is, such a small patient needs only 1 tablet of De-Nol per day. With greater weight, for example, if a child at 6 years old weighs 27 kg, the daily dose should be at least 216 mg, therefore, this patient is prescribed a double dose of 1 tablet.
• For children aged 8-12 years, the medication is prescribed one tablet twice a day.
• If the child is already 12 years old, a single dose can be increased to 2 tablets, then with a double intake the daily dose will be 4 tablets. You can also take the drug on 1 tablet at the reception, then you need to drink the medicine four times a day.
• The duration of treatment is from 4 to 8 weeks. For more than eight weeks, medication cannot be given, and within 2 months after completion of therapy, the child should not receive any bismuth preparations.

If a child takes bismuth subcitrate at a dosage greater than that recommended for a long time, this will adversely affect the condition of the kidneys. At the same time, renal function is quickly restored when the medication is withdrawn.

An excessively high single dose of the drug requires immediate gastric lavage and taking laxatives and sorbents. In severe conditions, antidotes and hemodialysis are prescribed to the child.

De-Nol can be combined with antibacterial drugs that have anti-Helicobacter activity. In this case, it is not recommended to combine the drug with tetracycline, since the absorption of this antibiotic under the action of bismuth worsens. It is additionally contraindicated to give the child any bismuth preparations during treatment.

You can buy De-Nol at a pharmacy without a prescription.paying an average of 500 rubles for a pack of 56 tablets. Keep the tablets at home should be at a temperature not higher than + 25 ° C. The shelf life of the drug is 4 years.

On the use of the drug in children with gastritis or ulcers, parents respond mostly well. The drug is praised for effective action, large packaging, a minimum of side effects. The disadvantages of funds often include its high cost and long-term use.

Other drugs based on bismuth subcitrate, such as Ulkavis or Novobismol, can replace the drug. Such medicines are also available in the form of coated tablets and are used from 4 years of age. Also, the doctor may prescribe such effective remedies for peptic ulcer or gastritis as Almagel, Omez, Phosphalugel other.

From the following video you can learn more about the preparations for the restoration of the stomach in children. Comments on the popular children's doctor Komarovsky.