What should be the urea in the blood during pregnancy is normal? Causes of deviations

Content

Pregnancy is a time when all the physiological processes in the female body proceed differently. This results in a modified hormonal background, which occurs during childbirth. Urea is an important clinical indicator that also changes during different periods of pregnancy.

What it is?

Protein metabolism is one of the most important in the body. Its activity increases significantly during fetal development of the baby. The final process of protein metabolism is accompanied by the formation of carbamides (urea) in the blood.

These substances are quite dangerous for the body. Their excessive accumulation can cause very dangerous pathologies for both the future mom and her baby. According to their chemical structure, these substances can be attributed to ammonia products.

Further, they are excreted through the kidneys and urinary tract. Thus, 90% of urea is excreted from the body. The remaining urea is removed through the skin. Such removal of degradation products of protein metabolism is very important. It helps to cleanse the body of toxic substances.

Due to various pathologies, the concentration of urea in the blood may vary. Deviations can be either upward or downward. The development of these conditions in the body lead a variety of causal factors.

Normal values

In order to determine the concentration of urea in the blood, biochemical analysis is carried out. To do this, take a small amount of venous blood.

This research is being carried out in the usual women's clinic, but also in a private laboratory. Decipher the results obtained must therapist. If necessary, the doctor may refer the patient to additional studies.

During different periods of pregnancy, the concentration of urea varies:

  • In the very first weeks from the moment of conception and until the end of the first half of pregnancy, this figure is 2.5-7.1 mmol / l.
  • In the third trimester of pregnancy, the concentration changes to 2.5-6.3 mmol / l.

Low urea and creatinine values

Urea in the blood can be lowered during pregnancy due to various pathologies of the internal organs of the expectant mother. The liver is an organ that is actively involved in protein metabolism.

Diseases that can trigger a low level of urea in the blood include: cirrhosis, hepatitis, tumors and tumors, as well as excessive use of certain drugs.

These conditions significantly reduce the formation of the final products of protein metabolism, which is manifested by a decrease in urea in the blood.

Pathology of the pituitary gland, accompanied by the development of acromegaly, can also contribute to the development of this condition. In this case, excessive release of somatotropic hormone leads to a decrease in blood urea. This biologically active substance is synthesized in the anterior half of the pituitary gland. Unfortunately, it is possible to carry out therapy of this pathology only with the help of surgical treatment.

Dietary habits are also becoming a common cause leading to a decrease in blood levels of urea.If the expectant mother consumes few protein foods, this can lead to the development of this pathology in her. A pathological decrease in the concentration of urea in the blood occurs in women practicing vegetarian style food.

Urea can also be reduced in women who use improper diets or fasting. In this case, protein metabolism is also significantly impaired. Before making recommendations, a specialist should pay attention to the diet of a woman.

Kidney disease, accompanied by various functional disorders, can trigger a decrease in urea blood. Such a pathological condition is nephrotic syndrome. In this case, other related changes are also detected in the blood - hypoalbuminemia, hypoproteinemia and hyperlipidemia.

Diseases accompanied by increased release of antidiuretic hormone (ADH), increase the total volume of circulating fluid. This condition provokes a decrease in the concentration of urea in the blood.

Pregnancy is a physiological condition in which blood urea can decrease. The active work of the urinary system also contributes to the development of this state. Urea is significantly reduced, as a rule, in the 3rd trimester of pregnancy.

In order to separate the norm from the pathology, it is necessary to observe the course of pregnancy. For this, a woman preparing to become a mother should undergo biochemical tests to determine this indicator regularly.

Pathology of the intestine, accompanied by a violation of absorption, can also lead to the development of this condition. Doctors call this pathology malabsorption. Chronic enteritis or irritable bowel syndrome often leads to the development of this condition.

Chronic pancreatitis, accompanied by changes in the work of the pancreas, causes a significant violation of protein metabolism. In some cases, the development of this condition may also lead to and tumor formation of this organ.

The toxic effects of various substances also lead to a significant decrease in urea in the blood. Phosphorus or arsenic poisoning can cause a condition to develop.

A significant decrease in the level of urea in the blood can also be detected after dialysis. This procedure is prescribed to women with serious pathologies of the kidneys or other organs, accompanied by severe renal failure.

Increased blood urea

To increase this indicator can lead a variety of diseases of internal organs. Many of them are extremely dangerous. Most often, various pathologies of the kidneys and urinary tract, as well as liver disease, lead to the development of this condition.

When detecting an increase in blood levels of urea, doctors say about the presence of uremic syndrome. The development of this condition can lead a variety of reasons. In this situation, additional diagnostics are required, which will be aimed at establishing the cause of this pathology.

The accumulation of an excess of carbamides can lead to the development of a woman of many symptoms. A pregnant woman begins to tire more quickly, she has severe nausea and her appetite is disturbed. Often, future mothers complain of the appearance of increased gas formation in the stomach and the development of pain in the right side.

Some cancers and leukemias can cause the level of urea in the blood to increase significantly. This condition can also develop after severe burns or toxic poisoning.

Various bleeding can also contribute to the increase of urea in the blood. A reduction in the volume of circulating blood leads to this state, which causes an increase in urea in the blood.Also, the effects of various injuries and damage to internal organs lead to an increase in blood urea.

Intestinal obstruction is another pathology that can lead to the development of this condition.. It is extremely dangerous, as it requires urgent surgical treatment.

During pregnancy, the threat of life is great for both women and her baby. Without treatment, the prognosis for the development of this pathology is extremely unfavorable.

About why urea in the blood can be increased, and what could be the causes of this condition, see the next video.

Find out what happens to mother and baby every week of pregnancy.
Information provided for reference purposes. Do not self-medicate. At the first symptoms of the disease, consult a doctor.

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