Oxamp for children
Oxamp is one of the combined antibiotics. Is it prescribed to babies, how does it act on the children's body, and in what dosage is it used?
Release form and composition
Oxamp is made in the form of white capsules, packed in blisters or jars of 10 or 20 pieces.
The effect of the drug is provided immediately by two antibacterial substances - oxacillin (in the form of sodium salt) and ampicillin (in the form of trihydrate). They are presented in each capsule in a 1: 1 ratio (each dosage is 125 mg).
In addition, an injection form called Oxamp Sodium is also available. Such a drug is made in bottles containing white-yellow porous or powder mass. It contains ampicillin sodium, supplemented with oxacillin sodium (the ratio of such ingredients is 2: 1).
Vials with a capacity of 10 ml contain 200 mg of active substances, and the dosage of antibiotics in bottles with a volume of 20 ml is 500 mg.
Such bottles can be purchased both one by one and in a package of 2, 5, 10 or 50 pieces.
Operating principle
Oksamp has an antibacterial effect, and thanks to a combination of two compounds at once, the spectrum of the bactericidal action of this drug is very extensive. The drug destroys Shigella, Hemophilus sticks, Streptococcus, Salmonella, Staphylococcus, Meningococcus, Treponema, Actinomycetes and many other pathogens.
However, its effect does not apply to pseudomonads and many Protea strains.
Indications
The drug is prescribed for infections that are caused by bacteria that are sensitive to Oxamp. The drug is in demand for bronchitis, tonsillitis, cholecystitis, urethritis, wound infection, dysentery, pleurisy, sore throat, burns, pyelonephritis and many other pathologies.
It can also be prescribed for prophylaxis, for example, during surgical treatment or at the risk of pneumonia in newborns.
From what age is prescribed?
The injection form of the drug is used in the treatment of children of any age, including newborns.
Capsules are used in children older than three years.
Contraindications
Oxamp is not prescribed for hypersensitivity to its components, as well as for allergies to any beta-lactam antibiotics. In addition, this medicine is not given to children with lymphocytic leukemia or infectious mononucleosis.
Side effects
The use of Oxamp may trigger an allergic reaction in a child, for example, in the form of conjunctivitis, angioedema, skin rash or even anaphylactic shock. In some patients, due to the use of this antibiotic dysbacteriosis develops, vomiting appears, taste changes, the number of blood cells decreases.
If the medication is prescribed intramuscularly, then a frequent side effect is soreness at the injection site, and when injected into a vein, periphlebitis or phlebitis can develop.
Instructions for use
To determine the right amount of the child in capsules, you should know the weight of the patient. To calculate the dose, body weight in kilograms is multiplied by 100, if the child is 3-7 years old, or by 50, if his age is 7-14 years. The resulting number is the daily dosage of oxamp in milligrams (both antibiotics are taken into account), which is divided into 4-6 doses.
For a teenager over the age of 14, a single dose is 2-4 capsules, and 8-16 capsules are given per day for patients of this age.
To determine the dosage of injections Oxamp-sodium also need to take into account the weight and age of the child.If the medicine is prescribed to a newborn baby, a premature baby, or a baby up to a year old, then it needs from 100 to 200 mg per 1 kg of weight per day.
For children over the age of one year before the age of 7, to calculate the dose, multiply the weight in kg by 100 mg, and for children of 7-14 years old - by 50 mg. Further, this daily dosage is divided into 3-4 injections, which can be either intravenous (both jet and drip) and intramuscular.
Prick Oxamp Sodium should be at intervals of 6-8 hours. If the course of the disease is severe, the doctor may increase the daily dose by 1.5-2 times. If a child is older than 14 years old, then a single dose of injectable Oksamp will be the same as for adults - from 0.5 to 1 g (per day such a patient should receive 2-4 g of active substances).
For injection into the muscle, the contents of the vial should be diluted with sterile water (take 2 ml for 0.2 g and 5 ml for 0.5 g of the drug), but some physicians prescribe for anesthesia dilution with novocaine.
For intravenous injections, the powder is dissolved either with water for injection or with an isotonic solution in a volume of 10-15 ml.
If injections are given to a drip vein, the solvent is glucose solution, which, depending on the age of the child, is taken from 30 to 100 ml.
The duration of treatment with Oxamps is often 5-7 days, but sometimes the course can be extended to 2 weeks.
If the medication is given to a child intravenously, then such injections are given only for 5-7 days, and then transferred to intramuscular injections (if a longer course of therapy is required).
Overdose and drug interactions
No cases of an overdose of Oxamp have been reported. As for incompatibility with other drugs, the simultaneous use of laxative drugs, antacids or glucosamine will interfere with the absorption of Oksamp, and the use together with ascorbic acid, on the contrary, will accelerate absorption. Do not combine treatment with such an antibiotic with diuretic, allopurinol, indirect anticoagulants or NSAIDs.
It is contraindicated to prescribe Oxamp and together with bacteriostatic antimicrobial agents, for example, with sulfonamides, macrolides or tetracyclines, because they are antagonists. But drugs with a bactericidal effect, on the contrary, enhance the effect of treatment with Oxamp.
Such an effect is noted in cephalosporins, vancomycin, aminoglycosides and rifampicin.
Terms of sale and storage
Oxamp refers to prescription drugs, so it is obligatory to consult a doctor before purchasing it.
Shelf life of the drug - 2 years. While it has not expired, the medication should be kept in a place hidden from high humidity and sunlight.
The optimal storage temperature is below +20 degrees.
Oxamp-sodium dissolved in water for injection or glucose cannot be stored. This solution is used immediately after dilution.
Reviews
About the treatment of children Oxamps respond mostly well. According to parents, its use quickly lowers the temperature and eliminates other symptoms of infection.
The medicine is transferred by the majority of small patients normally, and its cost, according to moms, is low.
Analogs
Instead of oxamp, a drug with the same active compounds in a composition called Ampioks can be administered. It is available in capsules and is used in children over three years old in the same dosages and with the same indications as Oxamp.
In addition, when the child is infected, other antibacterial agents may be prescribed, for example, Amoxicillin, Panklav, Augmentin, Suprax or Zinnat.
However, to choose such an analogue without a doctor is unacceptable, since such preparations contain different active ingredients and have different age restrictions.
You can find out how to calculate the dose of medicine for a child from a well-known pediatrician doctor Komarovsky by watching the following video.
