Konvuleks syrup for children
When convulsive activity in children, valproic acid preparations are often prescribed, for example, Konvulex. Especially for children, it is produced in the form of a syrup. How does it affect the children's body and in what dose is prescribed?
Release form
Konvuleks syrup is a thick liquid with a bit of yellow or no color that smells like fruit. One bottle contains 100 ml of this medicine and is supplemented with a measuring syringe that helps accurately measure the right amount of syrup. The drug is also available in other forms - a solution for injections into a vein, capsules, drops and tablets.
Composition
The main component in Konvuleks syrup is valproic acid in the form of sodium valproate. The dosage of this compound in 1 ml of the drug is 50 mg. Auxiliary ingredients of the medicine are liquid maltitol, sodium cyclamate, peach and raspberry flavors, sodium chloride and other substances.
Operating principle
Valproic acid has an anticonvulsant effect, therefore Konvuleks represents a group of antiepileptic drugs. Once in the brain, the active component of the syrup inhibits an enzyme called GABA-transferase. The result of this effect is an increase in the level of gamma-aminobutyric acid (GABA) in the central nervous system cells.
Since this acid interferes with the spread of nerve impulses and acts as the main inhibitory mediator, the use of Konvuleks affects the development of seizures, reducing seizure activity and preventing seizures.
In addition, syrup treatment has a positive effect on the mood and mental state of patients. The drug also noted antiarrhythmic effect.
Indications
Konvuleks is used in all types of epilepsy, as well as in behavioral disorders associated with this disease. In children, this drug is also in demand for febrile convulsions and tics. It is used in manic-depressive syndrome.
How old is allowed?
Konvuleks in the form of a syrup is prescribed from 3 months of age. This form of the drug is considered the most optimal at the age of 6 years. Typically, the syrup is used in the treatment of patients younger than 11 years old, and then transferred to other forms containing the active substance in higher concentrations.
Contraindications
Syrup can not be taken:
- In severe diseases of the pancreas.
- With hemorrhagic diathesis.
- With pathologies of the liver with a pronounced disruption of the work of this organ.
- When hypersensitivity to any ingredient of medication.
- With a reduced level of platelets.
- With porphyria.
Children with kidney disease, enzymopathies, organic brain damage, mental retardation, hypoproteinemia or diseases of the bone marrow Konvuleks prescribed with caution.
Side effects
Treatment with Konvuleks can provoke tremor, nausea, changes in appetite, "flies" before the eyes, abdominal pain, anemia, skin rash and other symptoms. If they appear in a child, this should be reported to your doctor.
Instructions for use
- The drug is taken regardless of diet. Syrup give the child a syringe, offering to drink a small amount of water.
- The dosage of syrup per day is calculated by the weight of the small patient. In addition, take into account the type of therapy (whether Konvulex appointed independently or supplemented with other anticonvulsant drugs).
- For children weighing from 7500 g to 25 kg, the daily dose is 15 to 45 mg of active ingredient per 1 kg. On average, babies weighing 7.5-14 kg per day are given from 3 to 9 ml of syrup, children weighing 14-21 kg receive 6 to 12 ml of medicine, and children weighing 21-32 kg receive from 12 to 18 ml.
- If the weight of a small patient is more than 25 kg, treatment starts with 300 mg of active compound per day, which corresponds to 6 ml of syrup. Further, the dose is increased within 1-2 weeks until they get the desired effect (the disappearance of seizures).
- The calculated daily dose is divided into 2 or 3 doses.
- Treatment with Konvuleks is often long and can take many years. If seizures are absent for 2-3 years in a row, the dosage is gradually reduced. Dramatically refuse to receive syrup can not.
Overdose
Too high a dose of syrup causes vomiting, diarrhea, dizziness, decreased muscle tone, respiratory problems and other dangerous symptoms. For treatment, wash the stomach, give the child activated carbon, and in severe cases - support its vital functions and conduct hemodialysis.
Interaction with other drugs
If Convulex is prescribed along with drugs that inhibit the central nervous system, then their effect will increase. The use of hepatotoxic drugs syrup will increase the risk of a negative effect of the drug on the liver. The simultaneous appointment with phenytoin, carbamazepine, phenobarbital, erythromycin, zidovudine and many other drugs noted in the abstract, requires increased attention from the doctor.
Features of sale and storage
Konvuleks in syrup is sold by prescription and costs about 120-130 rubles per bottle. Store this drug at home is recommended at a temperature of + 15 + 25 degrees in a dry place. The shelf life of this form of medicine is 5 years.
Reviews
The use of Konvuleks in the form of syrup moms respond mostly positively. The tool is praised for effective action, noting that its reception helps with epilepsy and eliminates seizures. The advantages of the drug are also called low price, ease of use and pleasant taste, and negative side reactions are sometimes noted among the drawbacks.
Analogs
Other drugs based on valproic acid, such as Depakine syrup, granules Depakine Chronosphere, enteric tablets Enkorat or solution Valparin. However, even though they all include the same active substance, the analogue should be chosen together with the doctor.
You will learn more about the "Konvuleks" syrup in the following video.