Suspension "Biseptol" for children: instructions for use
With bacterial infections in children, sulfa drugs can be prescribed, the most famous representative of which is called Biseptol. Especially for children, this drug is available in suspension. What diseases helps this medicine and in what dose is it given to children?
Release form
Suspension Biseptol is a cream or white liquid, which has the smell of strawberries. In one dark glass bottle contains 80 ml of this drug.
Composition
The active substance in Biseptol is co-trimoxazole. This name combines two active ingredients at once, because in this medicine sulfamethoxazole is supplemented with trimetroprima, and the ratio of such substances is 5: 1.
In 100 ml of the liquid form of Biseptol contains 4 g of sulfamethoxazole (this is 200 mg per 5 ml of suspension) and 0.8 g of trimethoprim (per dose in 5 ml of the drug accounts for 40 mg of such a component). The dosage in 5 ml is considered for two substances at once, so it is 240 mg.
Among the auxiliary substances of Biseptol, water, Na-hydrogen phosphate, propyl and methyl parahydroxy benzoate, macrogol, carmellose Na, citric acid, propylene glycol and aluminosilicate Mg are present in the suspension. The smell and sweet taste of the medicine are provided by strawberry flavoring, maltitol and Na saccharinate.
Operating principle
The main components of Biseptol have an antimicrobial effect, affecting the formation of proteins in bacterial cells. Due to their influence, protein synthesis in microbial cells is disturbed, leading to their death. This effect is called bactericidal.
The drug is effective against:
- Intestinal sticks.
- Hemophilic sticks.
- Bacteria Haemophilus parainfluenzae.
- Moraksell cataris.
- Shigella.
- Citrobacter
- Klebsielle.
- Hafnium.
- Serratia.
- Yersinia
- Protea.
- Enterobacter.
- Cholera vibrio.
- Edwardsiel.
- Alcaligenes faecalis bacteria.
- Burkholderia.
Pneumocystas, Listeria, cyclospores, Brucella, Staphylococcus, Pneumococci, Providences, Salmonella and some other bacteria are also sensitive to Biseptol.
Mycoplasma, pseudomonads, pale treponema and tubercle bacillus possess resistance to the drug. Biseptol does not work on viruses, so this medicine is not prescribed for acute respiratory viral infections, as Dr. Komarovsky says. Microorganisms, which usually Biseptol acts on, are insensitive to medication; therefore, treatment is always recommended to start after sensitivity testing.
How to distinguish viral and bacterial infections, will tell Yevgeny Komarovsky in the video:
Indications
Biseptol is usually prescribed:
- With ENT infections - otitis media, sore throat, pharyngitis, laryngitis and others.
- With bacterial infection of the respiratory tract, for example, with pneumonia or bronchitis. The tool can be used to prevent infection of the lungs by pneumocysts.
- With cystitis and other infections of the excretory system.
- With travelers' diarrhea, shigellosis, cholera, typhoid and some other gastrointestinal infections.
- With brucellosis, toxoplasmosis, osteomyelitis, aktikomikoze and some other infections.
Perhaps you will be interested to see the release of the program E. Komarovsky, which details infectious diseases of the urinary tract in children:
At what age is it allowed to take?
The use of Biseptol at the age of 1 year is possible. Such a drug in the form of a suspension is prescribed to children older than 2 months. If the mother has HIV infection, the use of medication in an infant is acceptable after 6 weeks of age. From the age of 3, treatment is allowed not only in liquid form, but also pillsHowever, most often they are given to children over 6-7 years old, when the child can safely swallow this solid form.
Contraindications
Biseptol should not be given:
- With intolerance to such a drug and any of its components.
- In renal failure.
- In case of severe liver impairment.
- With a lack of glucose 6 phosphate dehydrogenase.
- When leukopenia and agranulocytosis.
- With B12-deficient or aplastic anemia.
If a small patient has bronchial asthma, porphyria, allergic diseases, problems with the thyroid gland or vitamin B9 deficiency, Biseptol is used very carefully.
Side effects
- There are allergies to Biseptol manifested by urticaria, erythema, pruritus, fever, skin rash, toxic necrolysis, serum sickness, angioedema and other pathologies.
- The drug can cause headaches, nervousness, apathy and dizziness. Occasionally, its administration leads to inflammation of the peripheral nerves, depression, meningitis, convulsions, and hallucinations.
- Child's digestive tract may respond to Biseptol reduced appetite, nausea, abdominal pain, stomatitis, increased activity of liver enzymes, diarrhea, cholestasis. Some patients develop colitis, pancreatitis, gastritis, or hepatitis.
- When treating Biseptol, cough and shortness of breath may appear as signs of allergic alveolitis. The drug also causes infiltrates in the lung tissue.
- Biseptol can negatively affect blood formation, provoking a decrease in leukocytes, neutropenia, anemia, eosinophilia, thrombocytopenia and other changes.
- Side effect of medication on the urinary system there is a malfunction of the kidneys or the development of nephritis.
- The drug can cause myalgia and arthralgia.
Instructions for use and dosage
The suspension is offered to children after meals and washed down with a sufficient amount of water. Single dose is determined by age:
Children 2-5 months | 2.5 ml (120 mg of active compound) |
A child from six months to 5 years | 5 ml (240 mg of active ingredient) |
Children 6-12 years old | 10 ml (480 mg of active substance) |
A child over 12 years old | 20 ml (960 mg of active ingredient) |
The duration of Biseptal therapy depends on the pathology. For example, with shigellosis, the medicine is given for 5 days, with cystitis - from 10 to 14 days, with bronchitis - 2 weeks, and with typhoid fever, the treatment can be several months. As a rule, the remedy is not given for less than five days, and from the moment when the symptoms of the disease disappear, therapy is continued for another 2 days.
The drug is given twice at an interval of 12 hours. If the infection is severe, the doctor may increase the dosage by 50%.
Overdose
Too high a dose of suspension provokes nausea, headache, intestinal colic, vomiting attack, drowsiness, fever, fainting, dizziness, hematuria, depression. If a Biseptol overdose is prolonged, it leads to jaundice, a megaloblastic form of anemia, as well as a decrease in the level of platelets and leukocytes.
Interaction with other drugs and food
- Biseptol has the ability to enhance the effect of treatment with indirect anticoagulants, methotrexate and hypoglycemic agents.
- When combined with phenytoin, its therapeutic effect and toxicity increases.
- The administration of Biseptol and diuretics increases the risk of reducing the number of platelets.
- Biseptol reduces the effectiveness of certain antidepressants.
- The drug should not be combined with drugs, which have a depressant effect on blood formation, as well as with naproxen and aspirin.
- In the nutrition of the child during the treatment with Biseptol, it is advised to limit the dishes from cabbage, beans, carrots, tomato and peas, as well as fat cheeses and other animal products.
- Before taking the drug should not eat dried fruits and beet dishes, as well as pastries, because such products are very quickly digested.
- The effect of Biseptol is partially neutralized with milk, therefore, it is impossible to take the medicine with this product.
Terms of sale
Biseptol Suspension can be obtained from a pharmacy by prescription. The average price of one bottle is 120-130 rubles.
Storage conditions
In order for Biseptol to retain its properties for the entire shelf life of 3 years, it must be stored at temperatures below 25 degrees Celsius. Storage should be kept out of reach of children, dry and unlit.
Reviews
Doctors treat Biseptal differently. Some pediatricians often prescribe it for bacterial infections to children of different ages, others believe that nowadays many microbes have lost sensitivity to this medicine, so they prefer to prescribe modern antibiotics for sore throats or cystitis. Most often, the drug is discharged if the pathogen has a sensitivity to co-trimoxazole.
In parents' reviews, one can see both the positive effect of Biseptol treatment for otitis, bronchitis and other diseases, as well as complaints about side effects, among which nausea, appetite deterioration and allergies are most common. Also, in some cases, the drug does not have the desired effect, so it must be replaced with another antibacterial drug.
Analogs
You can replace Biseptol in suspension for children with other drugs that have the same active ingredients:
- Bactrim suspension.
- Suspension Co-Trimoxazole.
Also, instead of syrup Biseptol, the doctor may prescribe other sulfonamides., but these drugs are produced mainly in tablet form, so they are used in children aged 2-3 years and older.
Depending on the reason, antibiotics can be a substitute for Biseptol.For example, in case of bronchitis, the pediatrician may prescribe Amoxicillin, Panklav or Sumamed. At the same time, it is not possible to replace Biseptol with such drugs by yourself, since to choose the right analogue taking into account all factors can only be a specialist.