Groprinosin for children: instructions for use

In the treatment of diseases caused by viruses, antiviral medications are used. At the same time, drugs that can affect the patient's immune system and enhance its response to the pathogen are especially in demand. One of them is Groprinosin. Is this remedy used in childhood and how is it used correctly?

The drug is manufactured by Gedeon Richter only in tablets, and Groprinosina does not have such forms as syrup, capsules or injections. The drug is sold in carton packs, inside which contains 20, 30 or 50 oblong white tablets. On one side of each of them there is a risk that, if necessary, the medication can be divided into equal halves.

The basis of the drug, providing Groprinosin therapeutic properties, is the compound "inosine pranobex." Each tablet of medicine includes this substance in a dose of 500 mg. Additional ingredients a bit. They are magnesium stearate, povidone K25 and potato starch. Thanks to these compounds, the tablets are solid and keep their shape.

Groprinosin has both an antiviral effect and an immunomodulatory effect. Taking this medication affects influenza viruses, herpes viruses, ECHO viruses, Epstein-Barr viruses, cytomegaloviruses and many other pathogens. The drug interferes with their reproduction by interfering with RNA replication processes.

The effect of the drug on the patient’s immune system consists of the following effects:

• Support for macrophage activity.
• Stimulation of the formation of antibodies and other substances involved in the immune response.
• Increased proliferation of white blood cells.
• Increased T-lymphocyte activity.
• Normalization of the ratio of immune cells in the blood.

Thanks to the use of the drug, the clinical symptoms of the infection go away faster and the patient’s body resistance increases.

Groprinosin is recommended to be taken with a weakened immune system under the influence of viral infections. Most often, these pills are prescribed for the defeat of herpes viruses, for example, when glips on lips, keratitis or severe chickenpox. They are also in demand for mononucleosis, influenza, papillomas, cytomegalovirus infection, parotiditis and other diseases.

Another reason to prescribe medication is such a rare, but severe pathology of the brain, as subacute sclerosing panencephalitis. Its development is associated with measles infection. Studies have shown that inosine pranobex can slow the progress of this disease and prolong the patient's life.

Treatment of children with Groprinosin is allowed from 3 years, however, the instruction contains an additional condition - the weight of the baby should not be less than 15 kilograms. If the weight of the sick child is less, it is better for him to prescribe another antiviral drug.

Tablets should not be drunk:

1. With increased sensitivity to any component.
2. With arrhythmias.
3. When urolithiasis or gout.
4. In chronic kidney diseases that lead to kidney failure.

In addition, the administration of the medication requires caution if the young patient has liver pathologies due to which the function of this organ has been violated.

When treating Groprinosin can occur:

• Negative symptoms of the central nervous system, which are manifested by fatigue, dizziness, deterioration of health or headaches. Occasionally, the child becomes nervous, cannot fall asleep, or, conversely, looks drowsy.
• Negative manifestations of the digestive tract in the form of reduced appetite, abdominal pain or nausea. Some patients' gastrointestinal tract responds to medication with vomiting, constipation, or stool liquefaction.
• Problems with the work of the liver. They can be detected at an early stage in a blood test that will show increased enzyme activity.
• Increased urine volume.
• Allergic reactions, such as skin rash, swelling, hives, or severe itching.
• Pain in the joints.

Also, tests of the child may show an increased concentration of urea.

• The child is given to swallow a pill and drink a small amount of water. If the baby does not succeed in this, the medicine is allowed to crush into powder, dilute with still water in a spoon and give to the little patient in this form.
• Usually, the frequency of Groprinosin intake is 3 times a day (with an equal interval of 8 hours), but it can be prescribed four times (with a pause between doses of 6 hours).
• The doctor calculates the dosage for the child individually according to his weight. Multiplying the body weight in kilograms by 50 mg, receive a daily amount of the drug. For example, a baby with a weight of 20 kg requires 20 * 50 = 1000 mg, which corresponds to two tablets. This means that the medicine can be given crumbs 4 times a day for half a tablet.
• If the doctor has diagnosed a severe infectious disease, the daily dose of Groprinosin can be increased to 100 mg of the active ingredient per kilogram of the patient’s body weight. The calculated dose is divided into 4-6 receptions. For example, a child weighs 50 kg, so he needs 50 * 100 = 5000 mg (10 tablets). In this situation, the patient can be given 2 tablets 5 times a day or 2.5 tablets four times a day.
• How long to take the medication depends on the course of the disease. If Groprinosin is prescribed for acute infection, then they drink it for at least 5 days, and when the symptoms of the disease have disappeared, they continue to take 1-2 more days, but the duration usually does not exceed two weeks. Chronic disease with recurrence is treated by courses, prescribing tablets for 5-10 days. After completing one course after 8 days, you can begin the next one, and the total duration of treatment is up to 30 days.

The manufacturer does not mention cases of drug overdose, but when taking a large number of tablets, gastric lavage and consultation with a specialist is recommended.

Interaction with other drugs:

1. The medicine has good compatibility with antibiotics and other antiviral agents.
2. The therapeutic effect of Groprinosin will be less if the child simultaneously takes immunosuppressants.
3. With the additional appointment of loop diuretics or allopurinol the risk of increasing the level of uric acid in the bloodstream due to the intake of Groprinosin increases.
4. Groprinosin affects the concentration in the blood and the rate of excretion of a drug such as zidovudine. This should be considered when determining the correct dosages.

To buy Groprinosin's packaging in a pharmacy, you first need to consult a doctor and take a prescription from him. The average price of a pack of 20 tablets is about 700 rubles, and for a box of 50 tablets you need to pay about 1400-1500 rubles.

Keep the medication at home should be in a place hidden from sunlight, where the pills will not be able to freely take a small child. Storage temperature should not be more than +25 degrees Celsius. The shelf life of the drug - 3 years.

About the admission Groprinosina children respond differently. Some parents and doctors call it effective, others insist on the absence of any action during a viral infection and are looking for a replacement for such a drug.

The therapeutic effect is often noticed in cases where the administration of Groprinosin began in the early days of the disease. When using tablets in children with herpes, mothers often note that new bubbles appeared less frequently, and relapses of the disease were significantly reduced.

The disadvantages of the drug include its high cost and uncomfortable shape. According to moms, swallowing pills for many children is hard, they are very large and are crushed with difficulty. In addition, they have an unpleasant bitter taste.

Full replacement Groprinosinu called a drug called Isoprinosine. He has the same active substance, the same release form and dosage per tablet. Indications for use, negative side effects, age restrictions and other contraindications for such drugs are the same. In addition, the drugs are in about the same price category.

If it is possible to give a child Groprinosin or Isoprinosine No, the doctor can replace such drugs with drugs with similar therapeutic effects:

• Syrup Amizonchikallowed from 3 years;
• Pills Kagocelused in acute respiratory viral infections and other diseases, as well as for prevention from 3 years of age;
• Capsules Ingavirinappointed at age 7;

• Syrup Orviremwhich is allowed for children over a year;
• Suspension Arbidolapplied from 2 years;
• Pills Amiksinthat give children over 7 years old.